Serum Tests

Serum tests are offered as profiles or as individual tests

Bullous Diseases

Basic Pemphigus - Pemphigoid Screen (PP Screen)
Tests on monkey esophagus for IgG and IgG4 antibodies by indirect immunofluorescence (IIF).

• Profile 1 (Pemphigus): tests on monkey esophagus for IgG and IgG4 antibodies by IIF and Dsg 1 and Dsg 3 ELISA.
• Profile 2 (Paraneoplastic pemphigus): tests on monkey esophagus for IgG, IgG1 & IgG4 antibodies by IIF plus complement IIF, IIF on rat bladder and Dsg 1 and Dsg 3 ELISA. Immunoblot with consultation.
• Profile 3 (Pemphigoid): tests on monkey esophagus and split skin for IgG & IgG4 antibodies by IIF and BP 180 plus BP 230 ELISA.

Dermatitis Herpetiformis & Celiac Disease

• IgA anti endomysial antibodies (AEmA) by indirect IF
• IgA tissue transglutaminase (tTG) antibodies by ELISA
• AEmA and tTG-ELISA

All positives filed for tracking IgA antibodies

Systemic Connective Tissue Diseases

• Profile A (Basic): ANA and Complement fixing ANA (CANA) titers and patterns on HEp2 cells, antibodies to Ro(SS-A) and La(SS-B).
• Profile B (Systemic LE Screen): ANA and Complement fixing ANA (CANA) titers and patterns on HEp2 cells , antibodies to nDNA, Ro(SS-A), La(SS-B), Sm and RNP.
• Profile C (Systemic Connective Tissue Diseases Screen): ANA and Complement fixing ANA (CANA) titers and patterns on HEp2 cells, antibodies to nDNA, Ro(SS-A), La(SS-B), Sm, RNP, Jo-1, Scl 70 and beta 2 glycoprotein I IgG.
• Profile D (Drug Induced LE/SLE Screen): ANA and Complement fixing ANA (CANA) titers and patterns on HEp2 cells, antibodies to nDNA, Ro(SS-A), La(SS-B), Sm, RNP and histone.
• Profile E (Systemic Sclerosis Screen): ANA and Complement fixing ANA (CANA) titers and patterns on HEp2 cells, antibodies to Scl 70, Sm and RNP.