Test Code #
CPT Code(s) #
Jo-1 (for Polymyositis & Dermatomyositis)
LE, other Connective Tissue Diseases
Type of Study:
Negative <20 Units
Weak Positive 20-39 Units
Moderate Positive 40-80 Units
Strong Positive >80 Units
Assay performed once per week. Report availability is one week from the time of specimen receipt.
Collect 5-10 ml of blood in a red top or serum separator tube. If possible, separate serum from clot and place into red capped tube provided with Beutner Laboratories collection kits. If separation facilities are not available, the blood can be sent in the tube used for collection.
Stable at ambient temperature during shipment. If sample is stored prior to shipment, it is stable refrigerated (2-8ºC) up to five days and frozen (-20ºC or lower) up to one year.
Jo-1 antibodies are seen in 20-40% of patients with dermatomyositis, polymyositis or mixed PM/DM. The presence of these antibodies may associated with pulmonary involvement in patients with myositis. Antibody titer may fluctuate with disease activity.