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Serum Tests

Serum tests are offered as profiles or as individual tests

 

Bullous Diseases

 

Basic Pemphigus - Pemphigoid Screen (PP Screen)
Tests on monkey esophagus for IgG and IgG4 antibodies by indirect immunofluorescence (IIF). 

  • Profile 1 (Pemphigus): tests on monkey esophagus for IgG and IgG4 antibodies by IIF and Dsg 1 and Dsg 3 ELISA

  • Profile 2 (Paraneoplastic pemphigus): tests on monkey esophagus for IgG, IgG1 & IgG4 antibodies by IIF plus complement IIF, IIF on rat bladder and Dsg 1 and Dsg 3 ELISA. Immunoblot with consultation. 

  • Profile 3 (Pemphigoid): tests on monkey esophagus and split skin for IgG & IgG4 antibodies by IIF and BP 180 plus BP 230 ELISA. 

Dermatitis Herpetiformis & Celiac Disease

  • IgA anti endomysial antibodies (AEmA) by indirect IF 

  • IgA tissue transglutaminase (tTG) antibodies by ELISA 

  • AEmA and tTG-ELISA 

All positives filed for tracking IgA antibodies 

Systemic Connective Tissue Diseases

  • Profile A (Basic): ANA and Complement fixing ANA (CANA) titers and patterns on HEp2 cells, antibodies to Ro(SS-A) and La(SS-B). 

  • Profile B (Systemic LE Screen): ANA and Complement fixing ANA (CANA) titers and patterns on HEp2 cells , antibodies to nDNA, Ro(SS-A), La(SS-B), Sm and RNP. 

  • Profile C (Systemic Connective Tissue Diseases Screen): ANA and Complement fixing ANA (CANA) titers and patterns on HEp2 cells, antibodies to nDNA, Ro(SS-A), La(SS-B), Sm, RNP, Jo-1, Scl 70 and beta 2 glycoprotein I IgG. 

  • Profile D (Drug Induced LE/SLE Screen): ANA and Complement fixing ANA (CANA) titers and patterns on HEp2 cells, antibodies to nDNA, Ro(SS-A), La(SS-B), Sm, RNP and histone. 

  • Profile E (Systemic Sclerosis Screen): ANA and Complement fixing ANA (CANA) titers and patterns on HEp2 cells, antibodies to Scl 70, Sm and RNP.

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