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Test #


CPT Code(s) #

88346 (for initial SES-ANA Screen); if positive, 88350 (for establishing end point titer), 86038 (HEp-2 Screen), and 86039 (if applicable, HEp-2 Pattern)

If Profile, Includes Tests:


Disease Name:

Chronic Ulcerative Stomatitis (CUS)

Type of Study:

Serum Studies


Indirect Immunofluorescence


Primate Esophagus/HEp-2

Reference Range:

Based upon selective reactions on substrates used in the differential assay.




Assay performed daily Monday-Friday. Report availability is within 48 hours from the time of specimen receipt.

Specimen Requirements:

Collect 5-10 ml of blood in a red top or serum separator tube. If possible, separate serum from clot and place into red capped tube provided with Beutner Laboratories collection kits. If separation facilities are not available, the blood can be sent in the tube used for collection.

Sample Stability:

Stable at ambient temperature during shipment. If sample is stored prior to shipment, it is stable refrigerated (2-8ºC) up to five days and frozen (-20ºC or lower) up to one year.

Clinical Relevance:

The detection of stratified epithelium specific antinuclear antibodies assists in the diagnosis of connective tissue disease, and/or chronic ulcerative stomatitis.

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